TIM-3/HAVCR2 Fc Chimera Protein, Human Cytokine & Cytokine Receptor interferon-γ release at high concentrations

interferon-γ release at high concentrations during islet infusion contributes to the stimulation of CXCL10 and the loss of up to 50% of the islet graft immediately following transplant

and is responsible for immunoglobulin isotype switching to IgG1 and IgE

NK cell receptor D Accession P26718-1 Amino Acid Sequence Phe78-Val216

with C-terminal 10*His SGTLKKVAGALDGSVTFTLNITEIKVDYVVWTFNTFFLAMVKKDGVTSQSSNKERIVFPDGLYSMKLSQLKKNDSGAYRAEIYSTSSQASLIQEYVLHVYKHLSRPKVTIDRQSNKNGTCVINLTCSTDQDGENVTYSWKAVGQGDNQFHDGATLSIAWRSGEKDQALTCMARNPVSNSFSTPVFPQKLCEDAATDLTSLRGGGGSGGGSHHHHHHHHHH Expression System HEK293 Molecular Weight 33-45kDa Purity >95% by SDS-PAGE Endotoxin <0

activates the OX40 signaling pathway which promotes a robust immune response

TIM-3/HAVCR2 Fc Chimera Protein, Human Cytokine & Cytokine Receptor interferon-γ release at high concentrationsProduct Specification Species Human Synonyms TIMD3, HAVCR2, FLJ14428, KIM3 Accession Q8TDQ0 Amino Acid Sequence Ser22 Arg200, with C terminal Human IgG1 Fc